Reply to: ‘The predictive value of the sperm chromatin structure assay (SCSA®)’—a response from the SCSA inventor
نویسندگان
چکیده
منابع مشابه
The predictive value of sperm chromatin structure assay.
INTRODUCTION Sperm chromatin integrity assessment has been suggested as a fertility predictor. The aim of this study was to examine the relationship between the results of sperm chromatin structure assay (SCSA) and the outcome of IVF, ICSI and intrauterine insemination (IUI). METHODS A total of 306 consecutive couples undergoing assisted reproduction were included. IUI was performed in 131, I...
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15 صفحه اولEnvironmental toxicants cause sperm DNA fragmentation as detected by the Sperm Chromatin Structure Assay (SCSA).
Studies over the past two decades have clearly shown that reproductive toxicants cause sperm DNA fragmentation. This DNA fragmentation can usually be detected prior to observing alterations of metaphase chromosomes in embryos. Thus, Sperm Chromatin Structure Assay (SCSA)-detected DNA damage is viewed as the molecular precursor to later gross chromosome damage observed under the light microscope...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2006
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/dei342